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2 722 981

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IPC

A61K31/506(2006-01-01)

A61K31/55(2006-01-01)

A61P33/06(2006-01-01)

(21) (22)

Application

2019145376, 2019-12-31

(24)

Start date

2019-12-31

(22)

Actual filing date

2019-12-31

(45)

Published

2020-06-05

(72)

Inventor

Morozova Lola FarmonovnaTurbabina Natalya AleksandrovnaStepanova Ekaterina ViktorovnaMaksimova Mariya SergeevnaKondrashin Anatolij ViktorovichSergiev Vladimir PetrovichMorozov Evgenij NikolaevichTarasov Vadim Vladimirovich

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Pervyj Moskovskij Gosudarstvennyj Meditsinskij Universitet Imeni I.M. Sechenova Ministerstva Zdravookhraneniya Rossijskoj Federatsii Universitet) Vo Pervyj Mgmu Im. I.M. Sechenova Minzdrava Rossii Universitet)

METHOD OF TREATING MALARIA USING A THERAPEUTIC COMBINATION OF TELOMERASE INHIBITORS (IIMATINIB MESILATE) AND ARTEMETHER Russian patent published in 2020 - IPC A61K31/506 A61K31/55 A61P33/06

Abstract RU 2722981 C1

FIELD: medicine; pharmaceutics.

SUBSTANCE: present invention refers to areas of pharmacology and medicine and can be used for chemotherapy of tropical malaria caused by Plasmodium falciparum agent, especially in cases of its drug-resistant forms. Method of treating malaria involves administering a combination of preparations of Artemether and Iimatinib mesilate once a day in dosages of 0.33 mg/kg and 0.25 mg/kg respectively for three days.

EFFECT: method provides higher clinical effectiveness in malaria by overcoming drug resistance and reducing side effects of the drugs used.

1 cl, 1 tbl

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RU 2 722 981 C1

Authors

Morozova Lola Farmonovna

Turbabina Natalya Aleksandrovna

Stepanova Ekaterina Viktorovna

Maksimova Mariya Sergeevna

Kondrashin Anatolij Viktorovich

Sergiev Vladimir Petrovich

Morozov Evgenij Nikolaevich

Tarasov Vadim Vladimirovich

Dates

2020-06-05—Published

2019-12-31—Filed