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2 493 159

(13)

(51)

IPC

C07D493/10(2006-01-01)

C07D323/02(2006-01-01)

C07D405/12(2006-01-01)

C07D407/12(2006-01-01)

A61K31/343(2006-01-01)

A61P33/06(2006-01-01)

(21) (22)

Application

2010121919/04, 2008-10-29

(24)

Start date

2008-10-29

(22)

Actual filing date

2008-10-29

(45)

Published

2013-09-20

(72)

Inventor

Vennerstrom Dzhonatan L.Don JujsjanCharman S'Juzan A.Uitlin SerdzhioSholle ZhakKrik Darren Dzh.Van SjaofanSriragkhavan KamaradzhChzhou Lin'Matil' JugCharman Uil'Jam N.

(73)

Holder

Mmv Medsins For Malehria Venchur

DISPIRO 1,2,4-TRIOXOLANES AS ANTI-MALARIA AGENTS Russian patent published in 2013 - IPC C07D493/10 C07D323/02 C07D405/12 C07D407/12 A61K31/343 A61P33/06

Abstract RU 2493159 C2

FIELD: chemistry.

SUBSTANCE: invention relates to dispiro 1,2,4-trioxolanes of formula: , where values of R are given in claim 1.

EFFECT: disclosed compounds unexpectedly enable to treat malaria with a single dose and provide preventive action against malaria and bilharzia.

17 cl, 6 tbl, 5 ex

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RU 2 493 159 C2

Authors

Vennerstrom Dzhonatan L.

Don Jujsjan

Charman S'Juzan A.

Uitlin Serdzhio

Sholle Zhak

Krik Darren Dzh.

Van Sjaofan

Sriragkhavan Kamaradzh

Chzhou Lin'

Matil' Jug

Charman Uil'Jam N.

Dates

2013-09-20—Published

2008-10-29—Filed