COMPOSITION FOR PREVENTING AND TREATING MYCOPLASMA HYORHINIS INFECTION AND METHOD OF PRODUCING SAID COMPOSITION Russian patent published in 2020 - IPC C07K14/30 C12N15/31 C12N15/63 A61K39/02 A61P31/04 

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, specifically to production of subunit vaccines against Mycoplasma hyorhinis, and can be used in medicine for preventing Mycoplasma hyorhinis infection. Disclosed is a vaccine composition based on XylF protein with SEQ ID NO: 1 in combination with an adjuvant. For recombinant production of the active principle of the vaccine, an expression vector is proposed to produce XylF in a prokaryotic expression system containing an expression element which contains a promoter and a ribosome binding site; a nucleotide sequence encoding said XylF; and a sequence coding a fusion partner selected from a group consisting of DsbC from E. coli, MsyB from E. coli, FklB of E. coli or a combination thereof.

EFFECT: invention provides achieving a strong immune response against Mycoplasma hyorhinis.

11 cl, 7 tbl, 3 ex, 2 dwg