FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention relates to a method of inhibiting GH, GHR, STAT5, SOCS and c-fos, which involves identification of a subject having a disease or condition with changes in expression/activity of genes/proteins related to GH, human GHR, STAT5 and SOCS, or on which changes in expression/activity of genes/proteins related to human GH, GHR, STAT5 and SOCS, can have a beneficial effect; and administering a therapeutically effective amount of a compound selected from the group consisting of:
and their pharmaceutically acceptable salts.
EFFECT: technical result is novel activity of existing compounds and a method of inhibiting thereof, which can be used in medicine for treating cancer, diabetes, immunosuppression, Alzheimer's diseases and diseases and conditions, in respect of which cell and tissue regeneration has a favorable effect.
17 cl, 23 dwg
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Authors
Dates
2020-07-10—Published
2016-02-12—Filed