FIELD: veterinary science; pharmaceutics.
SUBSTANCE: invention relates to veterinary science and pharmaceutics, specifically to a method of producing an inactivated animal dermatophytosis vaccine, according to which one performs sowing and separate cultivation of fungi cultures Microsporum canis, Microsporum qypseum, Trichophyton mentagrophytes, suspensions are prepared from grown cultures, concentration of fungal elements in each suspension is subtracted to 20–50 million in 1 ml, obtaining suspensions with the same content of fungal elements, mixing suspensions Microsporum canis, Microsporum qypseum, Trichophyton mentagrophytes in volume ratio of 2:1:2, twice washed, vaccine is considered immunogenic with total content of 20–50 million elements of fungi in 1 ml.
EFFECT: technical result consists in the immunogenicity and stability of the inactivated vaccine against animal dermatophytosis obtained using the disclosed method without using additional components, such as immunomodulating substances.
1 cl, 13 ex
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Authors
Dates
2020-07-23—Published
2019-12-16—Filed