CONJUGATE OF ANTIBODY AND DRUG, COMPOSITIONS BASED ON SAID CONJUGATE AND METHODS OF PRODUCING SAID CONJUGATE Russian patent published in 2020 - IPC C07K16/18 C12N9/10 A61K39/395 A61K47/68 

Abstract RU 2728235 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to production of a conjugate containing trastuzumab and a conjugated fragment consisting of monomethyl auristatin E (MMAE) and PEG-linker.

EFFECT: obtained conjugate can be used for treating a malignant tumor.

14 cl, 5 tbl, 12 ex, 18 dwg

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RU 2 728 235 C2

Authors

Khu Shon

Allen Lisha

Dates

2020-07-28Published

2015-06-11Filed