POLYPEPTIDES FOR TREATING ONCOLOGICAL DISEASES Russian patent published in 2020 - IPC C07K16/00 A61K38/00 A61P35/00 

Abstract RU 2728870 C2

FIELD: biotechnology; medicine.

SUBSTANCE: novel polypeptide sequences capable of inhibiting RAS-GTPase activity, including a functional fragment and a transport sequence, wherein the functional fragment includes the amino acid sequence SEQ ID NO: 1 or fragment SEQ ID NO: 2. Also described is use of said polypeptide for inhibiting the MAPK/ERK signaling pathway, as well as preparing a drug for treating lung cancer.

EFFECT: disclosed are polypeptides for treating oncological diseases.

7 cl, 30 dwg, 3 tbl, 7 ex

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Authors

Bozhenko Vladimir Konstantinovich

Kulinich Tatyana Mikhajlovna

Kudinova Elena Aleksandrovna

Shishkin Aleksandr Mikhajlovich

Solodkij Vladimir Alekseevich

Dates

2020-07-31Published

2017-10-12Filed