FIELD: biotechnology; medicine.
SUBSTANCE: novel polypeptide sequences capable of inhibiting RAS-GTPase activity, including a functional fragment and a transport sequence, wherein the functional fragment includes the amino acid sequence SEQ ID NO: 1 or fragment SEQ ID NO: 2. Also described is use of said polypeptide for inhibiting the MAPK/ERK signaling pathway, as well as preparing a drug for treating lung cancer.
EFFECT: disclosed are polypeptides for treating oncological diseases.
7 cl, 30 dwg, 3 tbl, 7 ex
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Authors
Dates
2020-07-31—Published
2017-10-12—Filed