PHARMACEUTICAL COMBINATION FOR TREATMENT AND/OR CHEMOSENSITISATION OF TUMOURS RESISTANT TO ANTICANCER DRUGS Russian patent published in 2010 - IPC A61K38/08 A61K31/555 A61K33/24 A61P35/00 

Abstract RU 2396974 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to molecular and experimental oncology and represents a pharmaceutical combination for simultaneous, separate or consecutive introduction which contains substrata phosphorylation site inhibitor CK2 which includes peptide P15 (CWMSPRHLGTC) together with a cytostatic agent pharmaceutically acceptably mixed with the appropriate carriers.

EFFECT: invention provides higher therapeutic index of current cytotoxic agent, by reducing an effective dose and natural toxicity exhibited by the medicines of such type, and evasion of chemical stability of a tumour with respect to conventional cytotoxic agents.

12 cl, 4 ex, 4 tbl, 2 dwg

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RU 2 396 974 C2

Authors

Perea Rodriges Sil'Vio Ehrnesto

Perera Negrin Jasser

Rodriges Ulloa Ar'Elis

Khil Valdes Kheovanis

Ramos Gomes Jassel'

Kastel'Janos Serra Lila Rosa

Betankur Nun'Es Lasaro Iram

Sanches Puehnte An'El'

Fernandes De Kossio Dorta Duke Khorkhe

Asevedo Kastro Boris Ehrnesto

Gonsales Lopes Luis Khav'Er

Besada Peres Vladimir

Alonso Daniel' Fernando

Gomes Daniel' Ehduardo

Dates

2010-08-20Published

2007-02-28Filed