FIELD: medicine.
SUBSTANCE: invention refers to medicine, particularly to dentistry, and can be used in therapy for treating inflammatory periodontium diseases. Disclosed agent for periodontitis treatment contains organosilicon glycerohydrogel, hydroxyapatite and an active additive, wherein as an active additive it contains a peptide ZP-2 (THR NLE NLE ALA SER HIS TYR LYS GLN HIS CYS PRO) with following ratio of components, wt%: hydroxyapatite 3–4, peptide ZP-2 (THR NLE NLE ALA SER HIS TYR LYS GLN HIS CYS PRO) 0.001–0.005, glycerol hydrogel composition Si(C3H7O3)4·6C3H8O3·28H2O – balance up to 100. What is also presented is a method of treating periodontitis, involving professional hygienic treatment of the oral cavity, antiseptic therapy and local drug therapy, wherein the local drug-induced therapy is carried out by inserting the above agent in the periodontal pockets in amount of 1.5–2.0 g in each periodontal pocket in the area of the patient's tooth with repeating the procedure five times in one day, wherein the agent from the periodontal canals is not removed.
EFFECT: use of group of inventions provides achieving stable effect of periodontitis treatment, including in severe disease and aggravation.
2 cl, 3 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR INCREASING PROLIFERATIVE ACTIVITY OF PERIPHERAL BLOOD LYMPHOCYTES | 2010 |
|
RU2465001C2 |
METHOD OF INCREASING BACTERICIDAL ACTIVITY | 2010 |
|
RU2448725C2 |
METHOD OF INCREASING REPAIR ACTIVITY | 2010 |
|
RU2455020C2 |
SYNTHETIC POLYPEPTIDE, METHOD FOR ITS PRODUCTION AND AGENT FOR CULTIVATION ON ITS BASE | 1994 |
|
RU2061699C1 |
GROWTH STIMULATING AGENT FOR HUMAN BONE MARROW CELLS | 1994 |
|
RU2136308C1 |
PREPARATION FOR TREATING PERIODONTITIS | 2015 |
|
RU2604128C1 |
METHOD OF DIAGNOSIS OF HEMOPOIESIS DEPRESSION | 1994 |
|
RU2136307C1 |
PEPTIDE HAVING LYNX1 PROTEIN ACTIVITY (EMBODIMENTS), PHARMACEUTICAL COMPOSITION FOR TREATING ANXIETY DISORDERS AND DEPRESSION OR CORRECTION OF COGNITIVE DISORDERS IN NEURODEGENERATIVE DISEASES, CONTAINING SAID PEPTIDE, AND METHOD OF TREATING AND CORRECTING SAID DISORDERS | 2020 |
|
RU2734649C1 |
PREPARATION FOR THE COMPLEX TREATMENT OF INFLAMMATORY PERIODONTAL AND ORAL MUCOSA DISEASES | 2021 |
|
RU2781848C1 |
MEANS FOR TREATING INFLAMMATORY DISEASES OF PARODONTIUM | 2014 |
|
RU2566073C1 |
Authors
Dates
2020-08-06—Published
2020-03-24—Filed