FIELD: medicine; pharmaceuticals.
SUBSTANCE: group of inventions relates to the pharmaceutical industry, specifically to a dosage form releasing an active substance in the individual's oral cavity, based on drotaverine. Dosage form releasing an active substance in the oral cavity of the subject, containing drotaverine as an active substance or its pharmaceutically acceptable salt in a therapeutically effective amount and a pharmaceutically acceptable carrier providing a form releasing an active substance in the oral cavity, characterized by that it contains drotaverine or its pharmaceutically acceptable salt in form of a complex with a taste masking agent in a weight ratio of 1:1 to 1:10, wherein the taste masking agent is cyclodextrin. Method for administering drotaverine into a subject, comprising placing the dosage form in an individual's oral cavity.
EFFECT: above described dose of drotaverine releases active component in oral cavity and has good taste characteristics.
5 cl, 5 tbl, 5 ex
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Authors
Dates
2020-08-11—Published
2019-05-29—Filed