METHOD OF PREPARING A PHARMACEUTICAL GEL COMPOSITION FOR TREATING PROCTOLOGIC DISEASES (VERSIONS) Russian patent published in 2020 - IPC A61K31/4422 A61K31/167 A61K31/517 A61K9/06 A61P1/00 A61P23/02 

Abstract RU 2730483 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to a method for preparing a pharmaceutical gel composition for treating hemorrhoids and anal fissures. Method of preparing a pharmaceutical gel composition for treating hemorrhoids and anal fissures containing: methyluracil, nifedipine, lidocaine in a certain ratio, in which in order to manufacture a ready pharmaceutical gel composition, it is necessary to prepare: gel containing methyluracil and lidocaine, by mixing methyluracil, lidocaine, carbopol, ethylenediaminetetraacetic acid, nipagin and triethanolamine with addition of water; nifedipine solution by mixing nifedipine with 96 % ethanol and polyethylene glycol-400 while thoroughly stirring; then, with thorough stirring, the nifedipine solution is added to the gel containing methyluracil and lidocaine to form a pharmaceutical gel composition (versions).

EFFECT: method described above simplifies preparation of a composition for treating hemorrhoids and anal fissures, having a stronger analgesic effect, with minimal reduction of therapeutic effect.

2 cl, 4 ex

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RU 2 730 483 C1

Authors

Barannikov Aleksandr Evgenevich

Dates

2020-08-24Published

2020-01-17Filed