FIELD: medicine; pharmaceutics.
SUBSTANCE: invention refers to medicine, pharmaceutics and veterinary science and can be used for producing chloramphenicol nanocapsules (levomycetin). Method of producing chloramphenicol nanocapsules involves adding chloramphenicol powder into the kappa-carrageenan suspension in methanol and 0.01 g of the E472c preparation used as a surfactant while stirring at 700 rpm. Then chloroform is added, obtained suspension of nanocapsules is filtered and dried. Weight ratio of core : shell in produced nanocapsules makes 1:1, 1:2 or 1:3.
EFFECT: invention allows to simplify and accelerate the process of producing nanocapsules and increase the output by mass.
1 cl, 3 ex
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Authors
Dates
2020-09-08—Published
2020-03-04—Filed