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2 619 328

(13)

(51)

IPC

A61K9/51(2006-01-01)

A61K31/545(2006-01-01)

A61K31/7036(2006-01-01)

A61K31/43(2006-01-01)

A61K47/36(2006-01-01)

B01J13/06(2006-01-01)

(21) (22)

Application

2014140357, 2014-10-06

(24)

Start date

2014-10-06

(22)

Actual filing date

2014-10-06

(45)

Published

2017-05-15

(72)

Inventor

Krolevets Aleksandr AleksandrovichBogachev Ilya AleksandrovichNikitin Kirill SergeevichBojko Ekaterina EvgenevnaMedvedeva Yana Vladimirovna

(73)

Holder

Krolevets Aleksandr Aleksandrovich

METHOD OF PRODUCING ANTIBIOTIC NANOCAPSULES IN GELLAN GUM Russian patent published in 2017 - IPC A61K9/51 A61K31/545 A61K31/7036 A61K31/43 A61K47/36 B01J13/06

Abstract RU 2619328 C2

FIELD: pharmaceutics.

SUBSTANCE: invention relates to chemical-pharmaceutical industry and represents a method drug encapsulation by non-solvent addition, characterized by the fast that the cores of nanocapsules are antibiotics, the envelope of them is gellan gum in ratio shell: nucleus 3:1, upon that gellan gum in hexane in the presence of the preparation E472 as a surfactant is complemented with antibiotic powder then butylchloride is added in droplets, obtained suspension of nanocapsules is filtered and dried.

EFFECT: invention allows to simplify and accelerate the process of producing nanocapsules and increase mass output.

1 cl, 2 dwg, 12 ex

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Authors

Krolevets Aleksandr Aleksandrovich

Bogachev Ilya Aleksandrovich

Nikitin Kirill Sergeevich

Bojko Ekaterina Evgenevna

Medvedeva Yana Vladimirovna

Dates

2017-05-15—Published

2014-10-06—Filed