DOSING REGIMES OF MELFLUFEN FOR CANCER DISEASES Russian patent published in 2020 - IPC A61K31/223 A61K31/573 A61K31/216 A61K47/26 A61K9/00 A61K9/08 A61K38/05 A61P35/00 

Abstract RU 2734930 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to use of melflufen (melphalan flufenamide; ethyl ether of L-melphalanyl-4-fluoro-L-phenylalanine) or a pharmaceutically acceptable salt thereof for treating or preventing multiple myeloma, where the melflufen dose of 35 to 45 mg (excluding the weight of any salt) is administered in the form of a parenteral dose at infusion rate of 1.2 to 1.4 mg/min.

EFFECT: dosing regimes of melflufen for cancer diseases are proposed.

22 cl, 6 dwg, 15 tbl, 3 ex

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RU 2 734 930 C2

Authors

Lindberg, Jakob

Dates

2020-10-26Published

2016-12-01Filed