FIELD: pharmaceuticals.
SUBSTANCE: invention relates to use of melflufen (melphalan flufenamide; ethyl ether of L-melphalanyl-4-fluoro-L-phenylalanine) or a pharmaceutically acceptable salt thereof for treating or preventing multiple myeloma, where the melflufen dose of 35 to 45 mg (excluding the weight of any salt) is administered in the form of a parenteral dose at infusion rate of 1.2 to 1.4 mg/min.
EFFECT: dosing regimes of melflufen for cancer diseases are proposed.
22 cl, 6 dwg, 15 tbl, 3 ex
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Authors
Dates
2020-10-26—Published
2016-12-01—Filed