METHODS FOR ADMINISTRATION OF 3-(4-AMINO-1-OXO-1,3-DIHYDROISOINDOLE-2-YL)PIPERIDINE-2,6-DIONE IN CERTAIN TYPES OF LEUKEMIA Russian patent published in 2010 - IPC A61K31/454 A61P35/00 

Abstract RU 2406501 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to medicine, namely to oncology, and can be used in leukemia treatment. The methods involve the course introduction of 3-(4-amino- 1-oxo-1,3-dihydroisoindole-2-yl) piperidine-2,6-dione 5 to 50 mg a day. Also the method under the invention involves the introduction of 3-(4-amino- 1-oxo-1,3-dihydroisoindole-2-yl) piperidine-2,6-dione with the second active agent.

EFFECT: use of the invention allows higher clinical effectiveness for leukemia ensured by the introduction of specified level doses of 3-(4-amino- 1-oxo-1,3-dihydroisoindole-2-yl) piperidine-2,6-dione which enable the inhibition of tumour cell proliferation and exhibit low toxicity.

22 cl, 2 tbl, 5 ex

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RU 2 406 501 C2

Authors

Zeldis Dzherom B.

Dates

2010-12-20Published

2006-10-03Filed