METHOD OF FORMING A LABORATORY MODEL OF PSORIASIS IN IMIQUIMOD-INDUCED INFLAMMATION IN EXPERIMENTAL ANIMALS Russian patent published in 2020 - IPC A61K31/4709 G09B23/28 

Abstract RU 2736000 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to dermatology, and can be used for medical purposes for studying pathogenesis of disease and action of external drug preparations. Method of forming a laboratory model of psoriasis in imiquimod-induced inflammation in experimental animals involves external application of imiquimod once day by 62.5 mg for 10 days on pre-shaved skin of back of Balb/c mice 7–8 weeks.

EFFECT: invention provides more indicative and reproducible model of psoriasis on laboratory animals.

1 cl, 2 ex, 3 dwg

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RU 2 736 000 C1

Authors

Zhukov Aleksandr Sergeevich

Zharun Evgenij Ruslanovich

Lavrov Nikanor Vasilevich

Khajrutdinov Vladislav Rinatovich

Samtsov Aleksej Viktorovich

Dates

2020-11-11Published

2020-04-03Filed