FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention refers to pharmaceutical industry, namely to a glucose-lowering transdermal plaster composition and can be used as a therapeutic agent for type 2 diabetes mellitus therapy. Transdermal plaster contains polyethylene glycol-400, ethyl alcohol 95 %, dimethylsulphoxide and plasdone K25, and the pharmacologically active component - glycazidum with the following ratio of components, g per 250 cm2: glycazide - 0.6; dimethylsulphoxide - 2.0; polyethylene glycol-400 - 2.0; plasdone K25 - 4.0; ethyl alcohol 95 % - 10.0.
EFFECT: disclosed patch has the capacity for prolonged storage with preservation of pharmacological activity for 2 years and soft form during storage with observance of temperature modes (not lower than +5 and not higher than +25 °C).
1 cl, 2 tbl
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Authors
Dates
2020-11-11—Published
2019-12-02—Filed