FIELD: immunology.
SUBSTANCE: disclosed is an antibody and its antigen-binding fragment, which specifically bind to the domain Pre-S1 of the surface antigen of hepatitis B virus (HBV). What is also described is a nucleic acid, an expression vector and a cell for expression of the antibody or its antigen-binding fragment.
EFFECT: this group of inventions can find application in prevention, treatment or diagnostics of HBV-infection.
9 cl, 1 dwg, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| ANTIBODIES BINDING CD3 | 2017 |
|
RU2779489C2 |
| SPECIFIC ANTIBODIES TO PD-L1 AND METHODS FOR THEIR APPLICATION | 2017 |
|
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| ANTIBODIES BINDING CTLA-4 AND APPLICATION THEREOF | 2018 |
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| METHOD FOR PREVENTION AND TREATMENT OF CANCER METASTASES AND BONE LOSS CAUSED BY CANCER METASTASES | 2007 |
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| POLYPEPTIDE LINKER FOR PRODUCTION OF MULTI-SPECIFIC ANTIBODIES | 2018 |
|
RU2776302C2 |
| ANTIBODIES AGAINST LIGAND-1 PROGRAMMED DEATH (PD-L1) AND APPLICATION THEREOF | 2017 |
|
RU2721582C1 |
| AIMED AT UPARAP ANTIBODY-DRUG CONJUGATES | 2017 |
|
RU2740311C2 |
| BIOLOGICAL MATERIALS FOR MODULATING IMMUNE RESPONSES | 2017 |
|
RU2770060C2 |
| PARTICLES CONJUGATED TO PEPTIDE | 2014 |
|
RU2813163C2 |
| ANTI-TIGIT ANTIBODIES AND METHODS OF USING | 2016 |
|
RU2732591C2 |
