CD3-SPECIFIC BINDING MOLECULES Russian patent published in 2024 - IPC C07K16/28 C07K16/30 C07K14/725 A61K39/00 

Abstract RU 2826453 C2

FIELD: biotechnology.

SUBSTANCE: disclosed are: a specific binding molecule that binds to CD3, a bifunctional binding molecule capable of binding to CD3 and a target cell, and methods for their preparation, pharmaceutical compositions for treating cancer and an infectious disease, nucleic acids coding specific and bifunctional binding molecules, expression vector, host cell for production of specific and bifunctional binding molecules. Also disclosed are methods of treating cancer and infectious disease.

EFFECT: invention is aimed at obtaining binding molecules which bind to CD3, and their use for treating cancer and an infectious disease in a subject.

27 cl, 4 dwg, 2 tbl

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RU 2 826 453 C2

Authors

Kanestraro, Martina

Dikmann, Nele

Kharper, Stiven

Kirk, Piter Benedikt

Malvejni, Rejchel

Odvajer, Ronan

Robertson, Ien Batler

Dates

2024-09-11Published

2020-01-30Filed