FIELD: clinical pharmacology; ophthalmic pharmacology.
SUBSTANCE: group of inventions is intended for ophthalmic application of a stable composition containing povidone-iodine. An ophthalmic composition contains an aqueous phase, an oil phase and povidone-iodine (PVP-I) in concentration of 0.2–1.0 % (weight/weight). Said oil phase consists of triglycerides with average length of carbon chain and is less than 3 % of total weight of composition. Said composition can be formulated into a pharmaceutical preparation for ophthalmic therapeutic use. Also provided is a method of treating ophthalmic pathological conditions involving administering said composition.
EFFECT: use of group of inventions provides physical and chemical stability and preservation of high content of free molecular iodine, as well as good tolerance of patients in treating eye diseases.
13 cl, 1 dwg, 10 tbl, 17 ex
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| DRUG DOSAGE FORM CONTAINING 6'-FLUORO-(N-METHYL-OR N, N-DIMETHYL-)-4-PHENYL-4',9'-DIHYDRO-3'H-SPIRO[CYCLOHEXANE-1, 1'-PYRANO[3, 4, b]INDOLE]-4-AMINE | 2011 |
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