COMBINATION OF TASQUINIMOD OR ITS PHARMACEUTICALLY ACCEPTABLE SALT AND PD-1 AND/OR PD-L1 INHIBITOR FOR USE AS A MEDICINAL AGENT Russian patent published in 2021 - IPC A61K31/4704 A61K39/395 A61K45/06 A61P35/00 

Abstract RU 2742373 C2

FIELD: pharmaceuticals.

SUBSTANCE: present invention refers to a combination containing Tasquinimod or its pharmaceutically acceptable salt and PD-1 and/or PD-L1 inhibitor for use as a drug. Disclosed is use of a combination comprising Tasquinimod or a pharmaceutically acceptable salt thereof and an anti-PD-1 and/or PD-L1 antibody, for treating bladder cancer. What is also presented is a pharmaceutical composition containing said combination, a combined preparation, kit and method of treating bladder cancer using said combination.

EFFECT: technical result is the disclosed combination of Tasquinimod or its pharmaceutically acceptable salt and the anti-PD-1 and/or PD-L1 antibody blocks the tumor proliferation in a synergetic way.

23 cl, 9 dwg, 7 ex

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RU 2 742 373 C2

Authors

Soares Khose Amauri

Shetaj Erik

Nekl Dzhessika

Shmidlen Faben

Dates

2021-02-05Published

2016-02-16Filed