FIELD: medicine.
SUBSTANCE: set of inventions relates to medicine, in particular to the use of regulator of neutrophil activation. Use of a regulator of neutrophil activation including batroxobin as an active ingredient: to inhibit neutrophil degranulation, to inhibit Mac-1 expression by neutrophils, to inhibit the formation of NETs by neutrophils, to inhibit the transendothelial migration of neutrophils as well as to treat diseases caused by activation of neutrophils which are selected from a group consisting of sepsis, acute respiratory distress syndrome, acute pancreatitis and acute lung disorder.
EFFECT: said solution enables regulating neutrophil activation for suppressing inflammatory reaction.
5 cl, 6 dwg, 3 tbl, 5 ex
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Authors
Dates
2021-02-05—Published
2018-01-12—Filed