REGULATOR OF NEUTROPHIL ACTIVATION Russian patent published in 2021 - IPC A61K38/48 A61P1/18 A61P7/00 A61P11/00 A61P31/04 

Abstract RU 2742417 C1

FIELD: medicine.

SUBSTANCE: set of inventions relates to medicine, in particular to the use of regulator of neutrophil activation. Use of a regulator of neutrophil activation including batroxobin as an active ingredient: to inhibit neutrophil degranulation, to inhibit Mac-1 expression by neutrophils, to inhibit the formation of NETs by neutrophils, to inhibit the transendothelial migration of neutrophils as well as to treat diseases caused by activation of neutrophils which are selected from a group consisting of sepsis, acute respiratory distress syndrome, acute pancreatitis and acute lung disorder.

EFFECT: said solution enables regulating neutrophil activation for suppressing inflammatory reaction.

5 cl, 6 dwg, 3 tbl, 5 ex

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RU 2 742 417 C1

Authors

Masuda, Haruchika

Asahara, Takayuki

Senga, Hirobumi

Dates

2021-02-05Published

2018-01-12Filed