METHOD FOR DETERMINATION OF FUNCTIONAL FIBRINOGEN Russian patent published in 2018 - IPC G01N33/86 

Abstract RU 2669796 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine and relates to method for determining functional fibrinogen comprising the examination of a whole blood sample by thromboelastography. Heparinized blood and batroksobin are introduced into a cuvette for thromboelastography, followed by thromboelastography, determining the maximum amplitude parameter (MABatrox) on a thromboelastogram, and the concentration of functional fibrinogen (FFBatrox) is calculated by the formula: FFBatrox = 0.1153 × MABatrox + 0.5903, where FFBatrox – concentration of functional fibrinogen (g/l), MABatrox – maximum amplitude on thromboelastogram with heparinized blood and batroksobin (mm), 0.1153 and 0.5903 – conversion factors.

EFFECT: invention provides increase in accuracy of determining the concentration of functional fibrinogen at the maximum amplitude of thromboelastogram of heparinized blood, in which the formation of a fibrin clot is induced by the addition of batroxobin.

1 cl, 4 ex, 10 dwg

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RU 2 669 796 C1

Authors

Polevodova Olesya Alekseevna

Galstyan Gennadij Martinovich

Berkovskij Aron Leonidovich

Sergeeva Elena Vladimirovna

Dates

2018-10-16Published

2017-10-30Filed