REPRESENTATIVE DIAGNOSIS Russian patent published in 2021 - IPC G01N33/50 A61K31/00 G01N33/574 C12Q1/68 G01N1/28 

FIELD: diagnostics.

SUBSTANCE: invention relates to a method for preparing a tumor tissue sample. A method for preparing a tumor tissue sample for determining a phenotypic profile of a tumor tissue sample, which involves: homogenisation of a tumor tissue sample; reconstructing a homogenized sample to obtain a homogenate, wherein said homogenate comprises substantially homogeneous cell structures, where the ratio of the cell structures in the homogenate subgroup is substantially similar or equal to the ratio of the cell structures in the tissue sample; analysis of homogenate cell structures; determining phenotypic profile of tumor tissue.

EFFECT: method described above enables higher detection of mutations from cancer tissues compared to histological sections taken from FFPE units of the same tissue.

1 cl, 55 dwg, 24 tbl, 12 ex