IDENTIFICATION OF TUMOUR-ASSOCIATED ANTIGENS FOR DIAGNOSTICS AND THERAPY Russian patent published in 2018 - IPC A61K39/00 A61K39/395 A61P35/00 

Abstract RU 2644686 C2

FIELD: pharmacology.

SUBSTANCE: antigen has a sequence encoded by the nucleic acid of SEQ ID NO: 1, and the composition comprises an effective amount of an antibody binding to the said antigen. This invention also discloses a method for diagnostics of these cancers, comprising detection or determination of the amount of antigen in a biological sample taken from a patient. In this case, the increased amount of this antigen in comparison with a patient who does not have the said tumour or cancer indicates the presence of the said tumour or cancer. The invention also discloses a kit for detection of the expression of the said antigen in a biological sample of a patient.

EFFECT: invention, through the detection of this antigen in a number of cancers, makes it possible to discover new methods for their treatment and diagnosis.

25 cl, 31 dwg, 16 tbl, 16 ex

Similar patents RU2644686C2

Title Year Author Number
ANTIBODIES AGAINST CLAUDIN 18.2 FOR CANCER DIAGNOSIS 2013
  • Sakhin Ugur
  • Tyurechi Ezlem
  • Mitnakht-Kraus Rita
  • Vel Shtefan
RU2661772C2
TOM34 GENE RELATED TO COLON CANCER 2006
  • Nakamura Jusuke
  • Furukava Joiti
  • Takhara Khideaki
  • Tsunoda Takuja
  • Matsusima Satosi
RU2526196C2
GENE TOM34 ASSOCIATED WITH CANCER OF LARGE INTESTINE 2006
  • Nakamura Jusuke
  • Furukava Joiti
  • Takhara Khideaki
  • Tsunoda Takuja
  • Matsusima Satosi
RU2449020C2
MODIFIED CELLS WITH CHIMERIC ANTIGEN RECEPTOR FOR TREATING CANCER EXPRESSING CLDN6 2020
  • Sahin, Ugur
  • Oehm, Petra
  • Rengstl, Benjamin
  • Reinhard, Katharina
  • Michel, Kristina
RU2826058C2
INDIVIDUALISED VACCINES FOR CANCER 2012
  • Sakhin Ugur
  • Krajter Sebastyan
  • Diken Mustafa
  • Dikmann Yan
  • Kozlovski Mikhael
  • Britten Tsedrik
  • Kestl Dzhon
  • Lever Martin
  • Renard Bernkhard
  • Omokoko Tana
  • De Graf Jokhannes Khendrikus
RU2670745C9
VACCINE COMPOSITIONS AND METHODS OF USE THEREOF 2010
  • Daftarian Piruz Mokhammad
  • Serafini Paolo
  • Lemmon Vens Pol
  • Li Vej
  • Kejfer Ejndzhel
  • Blomberg Bonni Bet
  • Peres Viktor L.
RU2600798C2
ANTIBODY BOUND WITH CARBONIC ANHYDRASE, AND USE THEREOF 2017
  • Moon Yoo Ri
  • Yoon Sangsoon
  • Hong Jeong Won
  • Kim Eun Jung
  • Choi Da Bin
RU2727682C1
VACCINE COMPOSITION 2014
  • Stojdl Devid F.
  • Bell Dzhon Kemeron
  • Likhti Brajan
  • Pol Dzhonatan
RU2684211C2
NOVEL PEPTIDES AND PEPTIDE COMBINATIONS FOR USE IN IMMUNOTHERAPY OF LUNG CANCER, INCLUDING NON-SMALL CELL LUNG CANCER (NSCLC) AND OTHER CANCERS 2016
  • Mahr, Andrea
  • Weinschenk, Toni
  • Schoor, Oliver
  • Fritsche, Jens
  • Singh, Harpreet
  • Wagner, Claudia
  • Leibold, Julia
  • Song, Colette
RU2723092C2
COMBINED THERAPY WITH CLAUDINE 18.2 ANTIBODIES FOR CANCER TREATMENT 2014
  • Sakhin Ugur
  • Tyurechi Ozlem
  • Mitnakht-Kraus Rita
  • Vel Shtefan
  • Yakobs Shtefan
  • Khajnts Kornelia
RU2699549C2

RU 2 644 686 C2

Authors

Sakhin Ugur

Tyurechi Ezlem

Kozlovski Mikhael

Uzener Dirk

Dates

2018-02-13Published

2013-03-26Filed