TETRAHYDROISOQUINOLINE DERIVATIVES Russian patent published in 2021 - IPC A61K31/47 C07D217/26 C07D471/04 C07D471/10 C07D491/20 C07D491/107 A61P21/00 

Abstract RU 2743424 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to novel compounds of tetrahydroisoquinoline derivatives of formula (I), as well as use and methods of treating a disease or condition sensitive to modulation of contraction of a skeletal muscle sarcomere.

EFFECT: obtaining novel compounds which modulate contractions of the skeletal muscle sarcomere and can be used for treating the mediated diseases.

32 cl, 10 dwg, 7 tbl, 167 ex

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Authors

Sato Ippei

Kamikubo Takashi

Miura Masanori

Matsushima Yuji

Tanaka Hiroaki

Shiina Yasuhiro

Yamaki Susumu

Saito Tomoyuki

Kiyohara Hiroshi

Ohe Munemichi

Mihara Kayoko

Morgan Bradley Paul

Malik Fady

Collibee Scott Emile

Ashcraft Luke

Lu Pu-Ping

Warrington Jeffrey Michael

Garard Marc

Dates

2021-02-18Published

2017-02-10Filed