CHIMERIC ANTIGEN RECEPTOR (CAR) WITH ANTIGEN-BINDING DOMAINS TO THE T-CELL RECEPTOR β- CONSTANT REGION Russian patent published in 2021 - IPC C07K16/28 C07K14/725 C12N5/10 C12N5/783 C12N15/63 A61K39/395

Abstract RU 2744046 C2

FIELD: immunology.

SUBSTANCE: application of cytolytic T-cell, cytolytic T-cell, CAR. Invention also discloses a nucleic acid molecule, an expression vector, a cell production method, a method of treating T-cell lymphoma or leukemia.

EFFECT: present invention can find further application in therapy of oncological diseases associated with malignant T-cells.

18 cl, 29 dwg, 6 tbl, 13 ex

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RU 2 744 046 C2

Authors

Pyule Marten

Masiosiya Pol

Dates

2021-03-02—Published

2015-03-05—Filed