IMMUNOGENIC COMPOSITIONS FOR IMMUNIZATION OF PIGS AGAINST CIRCOVIRUS TYPE 3 AND METHODS OF PRDUCTION AND APPLICATION THEREOF Russian patent published in 2021 - IPC C07K14/05 C07K14/01 C12N7/00 A61K39/12 

Abstract RU 2744193 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology. Described is a composition for the induction of immunological response against porcine circovirus type 3 comprising: at least one protein of porcine circovirus type 3, where said protein is encoded by a nucleotide sequence having at least 90% sequence homology with a sequence selected from the group consisting of SEQ ID No.3, SEQ ID No.5, SEQ ID No.7 or in which said protein has at least 90% sequence homology with a sequence selected from the group consisting of SEQ ID No.4, SEQ ID No.6, SEQ ID No.8, or any combination thereof; and veterinary acceptable carrier selected from the group consisting of solvent, dispersion medium, coating, stabilizing agent, diluent, conservant, antimicrobial agent, antifungal agent supporting isotonicity of an agent, agent, delaying absorption or any combination thereof. Described is also a composition for inducing an immunological response against porcine circovirus type 3 containing a nucleotide sequence selected from a group consisting of: a) a nucleotide sequence selected from a group consisting of SEQ ID No. 1, SEQ ID No. 3, SEQ ID No. 5, SEQ ID No. 7, SEQ ID No. 9 or one of their fragments; b) a homologous nucleotide sequence having at least 80% identity with the sequence defined in a); c) a complementary nucleotide sequence or RNA sequence corresponding to the sequence defined in a) or b); d) a nucleotide sequence modified by the sequence defined in a), b) or c); and e) a recombinant vector containing the nucleotide sequence defined in a), b), c) or d); and an additional component comprising a veterinary acceptable carrier selected from the group consisting of solvent, dispersion medium, coating, stabilizing agent, diluent, conservant, antibacterial agent, antifungal agent supporting isotonicity of an agent, agent, delaying absorption, or any combination thereof. In addition, disclosed is a composition for inducing an immunological response against porcine circovirus type 3, containing: a chimeric nucleic acid molecule including a plasmid nucleotide sequence containing the first part of the nucleic acid of porcine circovirus type 1 and the second part of the nucleic acid of porcine circovirus type 3 with said nucleic acid of porcine circovirus type 3 having at least 90% sequence homology with the sequence selected from the group consisting of SEQ ID No. 3, SEQ ID No. 5, SEQ ID No. 7 or in which said porcine circovirus type 3 nucleic acid encodes a protein having at least 90% sequence homology with a sequence selected from a group consisting of SEQ ID No. 4, SEQ ID No. 6, SEQ ID No. , or any combination thereof; and a veterinary acceptable carrier selected from a group consisting of a solvent, dispersion medium, coating, stabilizing agent, diluent, conservant, antibacterial agent, antifungal agent supporting isotonicity of an agent, agent, delaying absorption or any combination thereof. Disclosed is a method for inducing an immunological response against porcine circovirus type 3 including: administration to an animal in need of one of these compositions or any combination thereof.

EFFECT: invention expands the arsenal of means of prevention of porcine circovirus.

18 cl, 2 dwg, 6 ex

Similar patents RU2744193C2

Title Year Author Number
IMMUNOGENIC COMPOSITIONS FOR IMMUNIZATION OF PIGS AGAINST TYPE 3 CIRCOVIRUS AND METHODS OF THEIR PRODUCTION AND USE 2022
  • Hause, Ben
RU2803427C1
IMMUNOGENIC COMPOSITIONS FOR IMMUNISING PIGS AGAINST TYPE 3 CIRCOVIRUS AND METHODS FOR PRODUCTION AND APPLICATION THEREOF 2016
  • Hause, Ben
RU2771533C2
PCV2B DIVERGENT VACCINE COMPOSITION AND METHODS OF USE 2014
  • Nitzel Gregory Paul
  • Slade David Ewell
RU2662685C2
CHIMERIC PORCINE CIRCOVIRUS PCV2Gen-1Rep OF AND ITS APPLICATION 2009
  • Tszjujkhan' Nikol' M.
  • Mehn Sjan-Tszin'
RU2515901C2
METHODS AND COMPOSITIONS FOR IMMUNISATION OF PIGS AGAINST PORCINE CIRCOVIRUS 2008
  • Vu Stiven Kitu
RU2493254C9
PORCINE CIRCOVIRUS TYPE 3 (PCV3) VACCINES, PRODUCTION AND USE THEREOF 2020
  • Iyer, Arun
  • Hernandez, Luis, Alejandro
  • Patterson, Abby
  • Arruda, Bailey
  • Gimenez-Lirola, Luis, Gabriel
  • Anstrom, David, Michael
  • Vaughn, Eric, M.
  • Pineyro Pineiro, Pablo E.
RU2813989C2
FUSED POLYPEPTIDES AND VACCINES 2014
  • Sato, Takanori
RU2699006C2
POLYVALENT RECOMBINANT SWINE POX VIRUS 2017
  • Sato Takanori
  • Saito Sudzi
  • Komiya Yasutosi
RU2766008C2
RECOMBINANT VIRUS-LIKE CIRCOVIRUS CAPSID PARTICLE (VLP): COMPOSITIONS, METHODS AND USES 2020
  • Galarsa, Khose M.
  • Ven, Ke
  • Gavrilov, Boris
RU2817679C2
COMBINED VACCINE PCV/MYCOPLASMA HYOPNEUMONIAE 2013
  • Nittsel Gregori P.
  • Gelvin Dzhefri E.
  • Garret Dzhon Kejt
  • Kyulovik Dzhejms R.Ii
  • Riker Trejsi L.
  • Smattser Megan Mari
RU2615443C2

RU 2 744 193 C2

Authors

Hause Ben

Dates

2021-03-03Published

2016-10-17Filed