FIELD: biotech.
SUBSTANCE: invention relates to the field of biotechnology, namely to molecular biology, medical genetics and otorhinolaryngology. Disclosed are synthetic oligonucleotides for the diagnosis (genotyping) of the c-23+1G>A(rs80338940) mutation of the GJB2 gene in human biomaterial. The primers are combined into kits for detecting DNA in blood and other biological materials by polymerase chain reaction.
EFFECT: invention enables highly sensitive diagnostics of congenital hereditary deafness of a person in biological material. The use of this method also provides a highly sensitive and objective description of the human genotype with the determination of homozygous and heterozygous carriers of this mutation.
1 cl, 2 dwg, 2 tbl
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