FUSED SERPINE POLYPEPTIDES AND METHODS OF THEIR APPLICATION Russian patent published in 2021 - IPC C07K19/00 C07K14/81 C07K14/715 C07K16/24

Abstract RU 2746550 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to the field of biochemistry, in particular to an isolated fused protein containing at least one human alpha-1-antitrypsin polypeptide functionally associated with a modified human IgG4 Fc polypeptide.

EFFECT: invention is effective for inhibiting or down-regulating impaired expression or activity of serine protease in a subject in need thereof.

10 cl, 4 dwg, 4 ex

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RU 2 746 550 C2

Authors

Ekelman Brendan P.

Timmer Dzhon K.

Devero Kuinn

Dates

2021-04-15—Published

2015-10-27—Filed