ETHYL-2-(9-AMINOCHROMENO[4,3-D]PYRIMIDINE-5-YL)ACETATES AND THEIR PREPARATION METHOD Russian patent published in 2021 - IPC C07D491/52 C09K11/06 

Abstract RU 2746879 C1

FIELD: organic chemistry.

SUBSTANCE: present invention relates to the field of organic chemistry, namely to ethyl-2-(9-aminochromeno[4,3-d]pyrimidine-5-yl)acetate of the general formula I

R=Me (Ia) - ethyl-2-(9-amino-2-methyl-5H-chromeno[4,3-d]pyrimidine-5-yl)acetate; R=Ph (Ib) - ethyl-2-(9-amino-2-phenyl-5H-chromeno[4,3-d]pyrimidine-5-yl)acetate; R=NH2 (Ic) - ethyl-2-(2,9-diamino-5H-chromeno[4,3-d]pyrimidine-5-yl)acetate; R=MeS (Id) - ethyl-2-(9-amino-2-methylthio-5H-chromeno[4,3-d]pyrimidine-5-yl)acetate; R=PhCH2S (Ie) - ethyl-2-(9-amino-2-benzylthio-5H-chromeno[4,3-d]pyrimidine-5-yl)acetate. A method for producing ethyl-2-(9-aminochromeno[4,3-d]pyrimidine-5-yl)acetates of general formula I is also proposed.

EFFECT: new compounds that can be used as fluorescent dyes and probes are proposed.

2 cl, 1 tbl, 6 ex

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RU 2 746 879 C1

Authors

Chernov Nikita Maksimovich

Trukhanova Yuliya Aleksandrovna

Shutov Roman Vadimovich

Yakovlev Igor Pavlovich

Dates

2021-04-21Published

2020-10-06Filed