FIELD: biochemistry.
SUBSTANCE: invention relates to pharmacologically acceptable salts, represented by the structure of Formula (1), which can be used for the treatment of cancer or a precancerous condition or disorder. In Formula (1), Y is a pharmacologically acceptable organic or inorganic acid or acid residue, with the specified acid selected from HCl, methanesulfonic acid, trifluoroacetic acid (TFA), H2SO4 and H3PO4. The invention also relates to a pharmaceutical composition containing these salts and methods for the treatment of cancer or a precancerous condition, including in a subject who has an immunological disease or a disorder or dysfunction of organs.
EFFECT: invention may find application treatment of cancer or a precancerous condition or disorder.
22 cl, 5 dwg, 5 tbl, 24 ex
Title | Year | Author | Number |
---|---|---|---|
CYTARABINE CONJUGATES FOR TREATING CANCER | 2016 |
|
RU2708672C1 |
DELIVERY SYSTEMS FOR CONTROLLED DRUG RELEASE | 2016 |
|
RU2748992C2 |
CONJUGATES OF CYTOTOXIC AGENTS WITH PEPTIDES | 2007 |
|
RU2457218C2 |
DERIVATIVES OF VITAMINE B6 NUCLEOTIDES, ACYCLIC NUCLEOTIDES AND ACYCLIC NUCLEOSIDE PHOSPHONATES | 2012 |
|
RU2640582C2 |
NEW PSA-BINDING AGENTS AND THEIR USE | 2018 |
|
RU2787105C2 |
GLYCATED PEPTIDE GLP-1 | 2009 |
|
RU2543157C2 |
CONJUGATES OF LIGAND AND DRUGS | 2006 |
|
RU2470668C2 |
COMPOSITIONS AND METHODS RELATING TO DRUG CONJUGATES WITH ANTI-CD19 ANTIBODIES | 2019 |
|
RU2806333C2 |
TARGETING AMINOACID LIPIDS | 2013 |
|
RU2654210C2 |
POLYGLUTAMATE-AMINO ACID CONJUGATES AND METHODS | 2006 |
|
RU2472812C2 |
Authors
Dates
2021-05-06—Published
2016-12-01—Filed