THERAPEUTIC COMBINATIONS CONTAINING ANTI-FOLR1 IMMUNOCONJUGATES Russian patent published in 2021 - IPC A61K39/395 C07K16/28 A61P35/00 

Abstract RU 2749865 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to the field of biochemistry, in particular to a method for treating a patient with cancer expressing the folic acid receptor 1 (FOLR1), including the administration of an immunoconjugate that binds to FOLR1, as well as bevacizumab, carboplatin or pegidated liposomal doxorubicin (PLD) to a specified patient in need thereof. A method for treating a patient with FOLR1-expressing cancer is also disclosed, including the administration of an immunoconjugate that binds to FOLR1, as well as bevacizumab, bevacizumab and pegylated liposomal doxorubicin (PLD) or carboplatin and pegylated liposomal doxorubicin to a specified patient in need thereof.

EFFECT: invention can be effectively used in combination therapies targeting FOLR1-expressing tumor cells for the treatment of cancer.

36 cl, 12 dwg, 4 tbl, 13 ex

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RU 2 749 865 C2

Authors

Ponte Khose

Pinkas Yan

Ruis-Soto Rodrigo R.

Dates

2021-06-17Published

2016-09-16Filed