FIELD: immunology.
SUBSTANCE: disclosed are versions of the antibody and antigen-binding antibody fragments, which specifically bind to the epitope of folic acid receptor 1 (FOLR1). Described is a cell and a method of producing the antibody of the invention or its antigen-binding fragment. Also disclosed is a composition and a method for detecting FOLR1 expression in a sample, as well as a method for assessing the effectiveness of cancer therapy and methods for identifying a cancerous disease as likely to be treated or sensitive to treatment.
EFFECT: present invention can find further application in cancer diagnosis.
78 cl, 17 dwg, 17 tbl, 6 ex
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