REGIMEN AND METHODS FOR MULTIPLE SCLEROSIS TREATMENT USING OFATUMUMAB Russian patent published in 2021 - IPC A61K39/395 A61K9/00 C07K16/28 A61P25/28 

FIELD: medicine; neurology.

SUBSTANCE: group of inventions relates to the field of medicine, namely to neurology, and is intended for the treatment of multiple sclerosis. The method of treatment of multiple sclerosis includes a) administration of ofatumumab to a patient according to the loading dosing regimen at a dose of 20 mg of ofatumumab per day 0 or 1, Day 7 and Day 14; and b) administration of ofatumumab to a patient according to the maintaining dosing regimen in a dose of 20 mg of ofatumumab, starting from the fourth week of the dosing regimen and then continuing every four weeks. Another embodiment provides the use of ofatumumab for the treatment of multiple sclerosis.

EFFECT: use of the group of inventions makes it possible to increase effectiveness of multiple sclerosis treatment with a high safety profile.

15 cl, 5 dwg, 1 ex