METHOD FOR TREATMENT OF ADOLESCENT HYPOGONADOTROPIC HYPOGONADISM IN EXPERIMENT Russian patent published in 2021 - IPC A61K38/17 G09B23/28 A61P5/26 

Abstract RU 2750713 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to experimental medicine, endocrinology and andrology. The method for treatment of adolescent hypogonadotropic hypogonadism in an experiment includes intramuscular administration of a 0.1% solution of kisspeptin Kiss 10 at a dose of 500 mcg for 7 days to 2-months old adolescent laboratory animals with hypogonadotropic hypogonadism simulated by surgical removal of one gonad in newborn male rats on days 1 to 3 of postnatal life.

EFFECT: invention ensures high efficiency of treatment of hypogonadism based on accurate and controlled experimental model of the pathology.

1 cl, 1 dwg, 3 tbl

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Authors

Nikitina Irina Leorovna

Bajramov Alekber Azizovich

Yukhlina Yuliya Nikolaevna

Shabanov Petr Dmitrievich

Galagudza Mikhail Mikhajlovich

Grineva Elena Nikolaevna

Droblenkov Andrej Vsevolodovich

Masel Alisa Sergeevna

Zelener Artur Olegovich

Sarakaeva Lejla Ramazanovna

Plaksina Anna Olegovna

Dates

2021-07-01Published

2020-10-20Filed