FIELD: organic chemistry.
SUBSTANCE: invention relates to new nitrogen-containing bicyclic compounds of Formula (I), 
, wherein
R2 is 
or 
, in which R2A and R2B independently represent a substituted or unsubstituted bicyclo[1.1.1]pentil, and when the specified bicyclo[1.1.1]pentyl is substituted, it is substituted by one or more substituents selected from halogen and cyano, as well as pharmaceutical compositions and methods for the relief and/or treatment of cancer.
EFFECT: new nitrogen-containing bicyclic compounds of formula (I) have been obtained that have the ability to inhibit the activity of EGFR and are suitable for the treatment of cancer, when the cancer can be relieved or treated by inhibiting the EGFR activity.
36 cl, 4 tbl, 11 ex
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