TRICYCLIC JANUS KINASE 1 INHIBITORS, COMPOSITIONS, METHODS OF PRODUCTION AND USE THEREOF Russian patent published in 2024 - IPC C07D471/14 A61K31/437 A61P19/02 A61P35/00 A61P37/02

Abstract RU 2824349 C2

FIELD: medicine; pharmaceutics.

SUBSTANCE: invention relates to a compound having structural formula (VII), a pharmaceutical composition and use of the compounds in preparing a drug for treating a disease or disorder associated with JAK1.

EFFECT: novel compounds are obtained, which are safe and effective inhibitors of Janus kinase 1 and can be used in treating various diseases and disorders mediated by said activity, such as inflammatory diseases, immune-mediated diseases or cancer.

24 cl, 5 tbl, 50 ex

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RU 2 824 349 C2

Authors

Van, Chzhaokuj

Vaskes, Majkl Lourens

Dates

2024-08-07—Published

2019-11-01—Filed