DRUG FOR TREATMENT OF DISEASES CAUSED BY BACTERIA Russian patent published in 2021 - IPC C07D491/52 A61K31/519 A61P31/04 

FIELD: chemistry; pharmacology.

SUBSTANCE: invention relates to chemistry and pharmacology, namely to 7,9-dibromo-2,4-dioxo-1,2,3,4-tetrahydrochromeno[2,3-d]-pyrimidinium-10 of the formula 1, where X is selected from a group consisting of = CH₃COO- and HOOCCH₂CH₂COO-, or to its tautomeric, hydrate form, solvate and complex compound. The invention also relates to a drug and a pharmaceutical composition based on a compound of the formula 1 or its derivatives, the use of a compound of the formula 1 or its derivatives or a composition based on them, a method for the treatment of diseases caused by bacterial infections.

EFFECT: new derivatives of 7,9-dibromo-2,4-dioxo-1,2,3,4-tetrahydrochromeno[2,3-d]-pyrimidinium-10 are obtained, useful for the treatment of bacterial infections, for example, such as bacterial infections of oropharynx, skin, mucous membranes, urinary system, implants, respiratory system, gastrointestinal tract, osteomyelitis, sepsis, nosocomial and wound infections.

15 cl, 8 tbl, 10 ex