FIELD: medicine.
SUBSTANCE: invention relates to a medicinal agent with antiviral activity with respect to HIV infection and hepatitis B virus, which is a derivative of 2-chloro-5-phenyl-5H-pyrimido[5′,4′: 5,6]pyrano[2,3-d]pyrimidin-4-ol of general formula (I)  , where X is selected from a group of H, NO2, Hal, OMe; R1 is selected from: Cl, OH; R2 is selected from: Cl, SH, OH. Therapeutic agent can contain effective amounts together with a compound of formula (I) reverse transcriptase inhibitor, selected from Retrovir, or protease inhibitor selected from Lopinavir.
, where X is selected from a group of H, NO2, Hal, OMe; R1 is selected from: Cl, OH; R2 is selected from: Cl, SH, OH. Therapeutic agent can contain effective amounts together with a compound of formula (I) reverse transcriptase inhibitor, selected from Retrovir, or protease inhibitor selected from Lopinavir.
EFFECT: drug can be prepared in form of tablets or capsules for enteral reception or in form of lyophilic dried substance; or in form of rectal suppositories.
2 cl, 9 tbl, 6 ex
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|---|---|---|---|
| SUBSTANCE WITH ANTIVIRAL AND ANTIBACTERIAL ACTIVITY BASED ON DERIVATIVES OF 2,8-DITHIOXO-1H-PYRANO[2,3-D; 6,5-D']DIPYRIMIDINE AND THEIR 10-AZA-ANALOGUES | 2003 | 
 | RU2246496C1 | 
| METHOD FOR VIRUS CONTROLLING USING SUBSTANCE BASED ON 2,8-DITHIOXO-1H-PYRANO[2,3-d;6,5-d']DIPYRIMIDINE AND 10-AZA- ANALOGS THEREOF (VARIANTS) | 2005 | 
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Authors
Dates
2016-08-20—Published
2015-04-03—Filed