DRUG PREPARATION WITH ANTIVIRAL ACTIVITY (VERSIONS) Russian patent published in 2016 - IPC C07D491/147 A61K31/519 A61P31/14 A61P31/12 

Abstract RU 2595038 C1

FIELD: medicine.

SUBSTANCE: invention relates to a medicinal agent with antiviral activity with respect to HIV infection and hepatitis B virus, which is a derivative of 2-chloro-5-phenyl-5H-pyrimido[5′,4′: 5,6]pyrano[2,3-d]pyrimidin-4-ol of general formula (I) , where X is selected from a group of H, NO2, Hal, OMe; R1 is selected from: Cl, OH; R2 is selected from: Cl, SH, OH. Therapeutic agent can contain effective amounts together with a compound of formula (I) reverse transcriptase inhibitor, selected from Retrovir, or protease inhibitor selected from Lopinavir.

EFFECT: drug can be prepared in form of tablets or capsules for enteral reception or in form of lyophilic dried substance; or in form of rectal suppositories.

2 cl, 9 tbl, 6 ex

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RU 2 595 038 C1

Authors

Tets Viktor Veniaminovich

Tets Georgij Viktorovich

Krasnov Konstantin Andreevich

Dates

2016-08-20Published

2015-04-03Filed