FIELD: immunology.
SUBSTANCE: antibody is proposed that specifically recognizes human IL-13RA2, as well as a multifunctional immunoconjugate and a chimeric antigen receptor based on such an antibody. In addition, nucleic acid, an expression vector, a host cell, a virus, an immune cell, a pharmaceutical composition, a set and application are considered.
EFFECT: this invention can find further application in the therapy of tumors expressing human IL-13RA2.
20 cl, 24 dwg, 1 tbl, 12 ex
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