SUCCINIC ACID ESTER 5-HYDROXYADAMANTAN-2-ONE, WHICH PREVENTS THE DEVELOPMENT OF CARDIAC ARRHYTHMIAS Russian patent published in 2021 - IPC A61K31/225 A61P9/06 

Abstract RU 2757477 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to the use of succinic acid ether 5-hydroxyadamantan-2-one as a means to prevent the development of cardiac arrhythmias and stabilize the functional organization of cardiomyocytes of the sinus node. Succinic acid ether 5-hydroxyadamantan-2-one has a pronounced stabilizing effect on the sinus node, does not affect the electrical excitation between cardiomyocytes of the peripheral part of the node and working atrial cardiomyocytes, which keeps these cells under the protective influence of the sinus node and protects them from possible arrhythmic effects of pathological foci of ectopic electrical activity and can be useful both in the treatment of patients with cardiac arrhythmias that are combined with or complicated by cerebrovascular diseases, so it is in patients with disorders of cerebral circulation, which are accompanied by a disturbed rhythm of heart contractions.

EFFECT: wholesome effect of the specified substance is disclosed.

1 cl, 5 tbl, 7 dwg, 2 ex

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Authors

Mirzoyan Ruben Simonovich

Ganshina Tamara Sergeevna

Turilova Antonina Ivanovna

Seredenin Sergej Borisovich

Avdyunina Nina Ivanovna

Pyatin Boris Mikhajlovich

Zolotarev Valentin Ilich

Meshchaninova Aleksandra Denisovna

Rodina Anastasiya Sergeevna

Shagaleeva Olga Yurevna

Tikhonova Tatyana Aleksandrovna

Kamkin Andrej Glebovich

Sutyagin Pavel Valentinovich

Dates

2021-10-18Published

2020-04-29Filed