FIELD: medicine.
SUBSTANCE: invention refers to medicine, and concerns a pharmaceutical composition based on 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide L-glutaminate, having prolonged antiarrhythmic activity. Pharmaceutical composition contains as auxiliary substances magnesium sulphate, succinic acid or hydroxy-succinic acid, 2- (dimethylamino) ethanol and water.
EFFECT: invention enables increasing the antiarrhythmic and antifibrillator effect force when forming ischemic, reperfusion and electric pulse rhythm disorders in dogs and rats, as well as prolonging the pharmacological action.
1 cl, 5 tbl, 8 ex
Title | Year | Author | Number |
---|---|---|---|
PHARMACEUTICAL COMPOSITION WITH ANTIARRHYTHMIC ACTIVITY OF VARIOUS ETIOLOGIES | 2021 |
|
RU2783944C1 |
PHARMACEUTICAL COMPOSITION POSSESSING PROLONGED ANTIARRHYTHMIC ACTIVITY | 2012 |
|
RU2538674C2 |
METHOD OF PRODUCING A 2,6-DIMETHYLPHENYLACETAMIDE DERIVATIVE HAVING CEREBROPROTECTIVE ACTIVITY | 2018 |
|
RU2690506C1 |
APPLICATION OF LIDOCAINE DERIVATIVE WITH LOCAL ANESTHETIC ACTIVITY, FOR TERMINAL ANESTHESIA | 2016 |
|
RU2628811C1 |
AGENT POSSESSING ANTIARRHYTHMIC, ANTIFIBRILLATORY, ANTI-ISCHEMIC ACTION, AND BASED PHARMACEUTICAL COMPOSITION | 2011 |
|
RU2477130C1 |
AGENT POSSESSING ANTIARRHYTHMIC ACTION | 2019 |
|
RU2700263C1 |
2-AMINOCHROMEN DERIVATIVES EXHIBITING ANTI-TUMOR ACTIVITY; PHARMACEUTICAL COMPOSITIONS | 2018 |
|
RU2704262C1 |
DICYCLOHEXYLAMIDES OF N-SUBSTITUTED ALFA-AMINOCARBOXYLIC ACIDS HAVING ANTIARRHYTMIC AND ANTIFIBRILLARY ACTIVITY | 1994 |
|
RU2114821C1 |
N-1-[(4-FLUOROPHENYL)-2-(1-ETHYL-4-PIPERIDYL)-ETHYL]-4-NITROBENZAMIDE HYDROCHLORIDE EXHIBITING ANTIARHYTHMIC AND ANTIFIBRILLATORY ACTIVITY | 2009 |
|
RU2415128C2 |
VAGINAL ANTIARRHYTHMIC AGENTS FOR PELVIC PAIN TREATMENT | 2002 |
|
RU2345758C2 |
Authors
Dates
2019-08-19—Published
2018-05-23—Filed