2-(DIETHYLAMINO)-N-(2,6-DIMETHYLPHENYL)ACETAMIDE L-GLUTAMATE, HAVING PROLONGED ANTIARRHYTHMIC ACTIVITY, PHARMACEUTICAL COMPOSITION Russian patent published in 2019 - IPC A61K31/198 A61K31/167 A61P9/06 

Abstract RU 2697717 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, and concerns a pharmaceutical composition based on 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide L-glutaminate, having prolonged antiarrhythmic activity. Pharmaceutical composition contains as auxiliary substances magnesium sulphate, succinic acid or hydroxy-succinic acid, 2- (dimethylamino) ethanol and water.

EFFECT: invention enables increasing the antiarrhythmic and antifibrillator effect force when forming ischemic, reperfusion and electric pulse rhythm disorders in dogs and rats, as well as prolonging the pharmacological action.

1 cl, 5 tbl, 8 ex

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RU 2 697 717 C1

Authors

Skachilova Sofiya Yakovlevna

Korotonozhkin Aleksej Viktorovich

Aleshina Valentina Alekseevna

Gireva Nataliya Nikolaevna

Blinova Ekaterina Valerievna

Semeleva Elena Vladimirovna

Blinov Dmitrij Sergeevich

Zheltukhin Nikolaj Konstantinovich

Shilova Elena Vladimirovna

Dates

2019-08-19Published

2018-05-23Filed