METHOD FOR OBTAINING BIOLOGICAL PRODUCTS OF LIVING MICROORGANISMS WITH AN EXTENDED PERIOD OF PRESERVATION OF A HIGH TITER OF VIABLE CELLS BY IMMOBILIZATION IN GELS BASED ON SILANOL DERIVATIVES OF HUMIC SUBSTANCES Russian patent published in 2021 - IPC C12N1/20 

Abstract RU 2757600 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology and can be used to stabilize biological products containing live microorganisms. The method provides for the preparation of a gel from alkaline solutions of humic substances (HS) and 3-aminopropyltrialkoxysilane (APTS) by titration with an acetic acid solution to a pH value close to neutral, followed by the addition of APTS, immobilization of microorganism cells in gels by mixing a suspension of bacteria and gel in a given ratio, the stage of keeping for several hours until the gel thickens.

EFFECT: invention allows microorganisms being kept in an active state for a long time.

12 cl, 6 dwg, 1 tbl, 6 ex

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RU 2 757 600 C1

Authors

Nikolaev Iurii Aleksandrovich

Borzenkov Igor Anatolevich

Demkina Elena Vitalevna

Loiko Nataliia Gennadievna

Kanapatskii Timur Aleksandrovich

Perminova Irina Vasilevna

Volikov Aleksandr Borisovich

Khreptugova Anna Nikolaevna

Galuza Olesia Aleksandrovna

El-Registan Galina Ivanovna

Dates

2021-10-19Published

2021-01-27Filed