FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology and is a bidirectional promoter hCMV-CAG4, and recombinant vectors and a recombinant virus containing a bidirectional promoter hCMV-CAG4 functionally connected to the first transgene in one direction and to the second transgene in the opposite direction. The present invention also provides methods for the creation and use of such recombinant vectors and a recombinant virus.
EFFECT: invention allows inducing an immune response against at least two antigens.
17 cl, 5 dwg, 1 tbl, 4 ex
| Title |
Year |
Author |
Number |
| EFFICIENT AND BALANCED BIDIRECTIONAL PROMOTOR |
2017 |
- Wunderlich, Kerstin
- Vellinga, Jort
|
RU2745500C2 |
| CODON-OPTIMISED CDNA CODING HUMAN DYSFERLIN, GENETICALLY ENGINEERED CONSTRUCT, RECOMBINANT ADENOVIRUS AND PHARMACEUTICAL COMPOSITION FOR TREATING DYSFERLINOPATHIES |
2012 |
- Rizvanov Al'Bert Anatol'Evich
- Solov'Eva Valerija Vladimirovna
- Starostina Irina Georgievna
- Isaev Artur Aleksandrovich
- Deev Roman Vadimovich
- Shevchenko Konstantin Georgievich
|
RU2527073C2 |
| RECOMBINANT PSEUDO ADENOVIRAL PARTICLE BASED ON HUMAN BEING ADENOVIRUS GENOME OF 5-TH SEROTYPE FOR INDUCTION OF SPECIFIC IMMUNITY TO INFLUENZA VIRUS A OF H3N2 SUBTYPE AND METHOD OF ITS USE |
2012 |
- Ataullakhanov Rustam Ravshanovich
|
RU2507258C1 |
| RECOMBINANT PSEUDO ADENOVIRAL PARTICLE BASED ON HUMAN BEING ADENOVIRUS GENOME OF 5-TH SEROTYPE FOR INDUCTION OF SPECIFIC IMMUNITY TO INFLUENZA VIRUS A OF H1N1 SUBTYPE AND METHOD OF ITS USE AS COMPONENT FOR VACCINE PRODUCTION |
2012 |
- Ataullakhanov Rustam Ravshanovich
|
RU2507257C1 |
| RECOMBINANT PSEUDO-ADENOVIRUS PARTICLE BASED ON GENOME OF HUMAN ADENOVIRUS OF SEROTYPE 5, PRODUCING INFLUENZA HEMAGGLUTININ OF STRAIN A/Brisbane/59/2007(H1N1) AND METHOD OF ITS USE |
2012 |
- Ataullakhanov Rustam Ravshanovich
|
RU2523599C1 |
| ONCOLYTIC ADENOVIRUSES ENCODING BISPECIFIC ANTIBODIES, AS WELL AS METHODS AND APPLICATIONS ASSOCIATED THEREWITH |
2016 |
- Siurala, Mikko
- Liikanen, Ilkka
- Tahtinen, Siri
- Parviainen, Suvi
- Hemminki, Akseli
|
RU2725799C2 |
| RECOMBINANT PSEUDO ADENOVIRAL PARTICLE BASED ON HUMAN BEING ADENOVIRUS GENOME OF 5-TH SEROTYPE, PRODUCING HAEMAGGLUTININ OF INFLUENZA VIRUS OF B/Brisbane/60/2008 STRAIN AND METHOD OF ITS USE FOR INDUCTION OF SPECIFIC IMMUNITY TO INFLUENZA VIRUS B |
2012 |
- Ataullakhanov Rustam Ravshanovich
|
RU2507259C1 |
| ADENOVIRUS/ALFAVIRUS HYBRID VECTOR FOR EFFECTIVE ADMINISTRATION AND EXPRESSION OF THERAPEUTIC GENES IN TUMOR CELLS |
2005 |
- Tsjan' Chehn
- Guan' Min'
- Smerdou Pikazo Kristian
- Pr'Eto Val'Tuehn'Ja Khesus
|
RU2394104C2 |
| SIMIAN ADENOVIRUS NUCLEIC ACID- AND AMINO ACID-SEQUENCES, VECTORS CONTAINING SAME, AND USE THEREOF |
2010 |
- Kolloka Stefano
- Nikosija Alfredo
- Korteze Rikkardo
- Ammendola Virdzhinija
- Ambrozio Marija
|
RU2604815C2 |
| EXTENDED ADOPTIVE CELL THERAPY |
2014 |
- Khemminki, Akseli
- Vyakhya-Koskela, Markus
- Tyakhtinen, Siri
- Cherullo, Vinchentso
|
RU2703438C2 |
