METHOD FOR ASSESSING THE INTERNAL STRUCTURE OF ATHEROMATOUS PLAQUES BY MEANS OF INTRAVASCULAR OPTICAL COHERENCE TOMOGRAPHY Russian patent published in 2021 - IPC A61B5/255 

FIELD: medicine.

SUBSTANCE: invention relates to the field of medicine, namely, to diagnostics of the cardiovascular system. Tissues are classified according to the intensity of the interference signal and the value of the Young's modulus. The data on the optical and biomechanical properties of the structures of the blood vessel walls with atheromatous plaques are therein taken into account. The classification by the intensity of the interference signal is preliminary. The classification by the Young's modulus is used to clarify the results of the preliminary classification. The classification of tissues by the intensity of the interference signal is therein conducted after clearing the initial data from noise using threshold restriction, bandpass filtering and morphological processing. A pulse wave is used as a deforming impact when assessing the value of the Young's modulus, and the value of the deforming impact of the pulse wave is estimated by the drop in the blood pressure between the systole and diastole in the studied blood vessel, accounting for the direction of the blood flow rate vector. The blood pressure and the blood flow rate are obtained from an intravascular overpressure sensor. Absolute displacements in the wall of the studied blood vessel and the longitudinal dimensions of the deformed area are calculated based on control points, the area of the deforming impact is considered equal to the scanning area of the used intravascular probe.

EFFECT: method provides a possibility of increasing the accuracy of assessing the internal structure of atheromatous plaques by means of simultaneous use of medical data of various ranges, in particular, information on the optical, and most importantly, biomechanical properties of the studied blood vessel wall.

1 cl, 1 dwg