COMPLEX OF MYELIN LIPIDS OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM OF ANIMALS FOR TREATMENT AND PREVENTION OF NEURODEGENERATIVE DEMYELINATING DISORDERS AND METHODS FOR ITS APPLICATION Russian patent published in 2021 - IPC A61K35/30 A61K35/32 A61P25/28 A61K47/44 

FIELD: pharmaceutics.

SUBSTANCE: group of inventions relates to the pharmaceutical industry, namely to the use of a complex of animal myelin lipids for the preparation of a drug for the treatment or prevention of neurodegenerative demyelinating damage to nervous tissue, to a pharmaceutical composition, as well as to a method for the treatment or prevention of neurodegenerative demyelinating damage to nervous tissue. Application of a complex of animal myelin lipids is proposed, including lipid metabolites, cholesterol, phospholipids, growth and differentiation factors of nervous tissue, essential fatty acids, obtained by drying tissues of the central or peripheral nervous system of animals in frozen form under vacuum, adding 70 % ethyl alcohol in the amount of 10 % by volume, followed by extraction by supercritical CO₂ extraction at a pressure of 680-800 bar and a temperature of 80°C for the preparation of a drug for the treatment or prevention of neurodegenerative demyelinating damage to nervous tissue. A pharmaceutical composition for the treatment or prevention of neurodegenerative demyelinating damage to nervous tissue contains therapeutically effective amount of a complex of animal myelin lipids and a pharmaceutically acceptable carrier containing a fat base. A method for the treatment or prevention of acute neurodegenerative demyelinating damage to the nervous tissue in a patient is also proposed.

EFFECT: above-described group makes it possible to effectively treat and prevent acute neurodegenerative demyelinating damage to the nervous tissue in the patient, without undesirable side reactions and restrictions in use.

23 cl, 5 ex