LIPOSOMES CONTAINING OLIGOPEPTIDES - FRAGMENTS OF MYELIN BASIC PROTEIN, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATING MULTIPLE SCLEROSIS Russian patent published in 2012 - IPC A61K9/127 A61K38/02 A61K38/17 C07K14/47 A61P37/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions relates to medicine. Substance of the inventions involves monolamellar liposomes of the size of 100-200 nm consisting of a mixture containing 1 weight fraction of tetramannosyl-tri-L-lysine-diopeoyl glycerol and 99 weight fraction of 2,3-dipalmitole-Sn-glycero-phosphatidylcholine, and containing three oligopeptides with their sequence relevant to the sequences of the fragments: 46-62, 124-139 and 147-170 myelin basic protein. What is offered as an agent for multiple sclerosis is a pharmaceutical composition containing monolamellar liposomes as an active ingredient, as well as a method of treating multiple sclerosis involving the introduction of said pharmaceutical composition into the patient.

EFFECT: preparing the liposomes containing oligopeptides - fragments of myelin basic protein, the pharmaceutical composition and developing the method of treating multiple sclerosis.

5 cl, 7 ex, 1 tbl