FIELD: pharmaceutics.
SUBSTANCE: group of inventions relates to a liquid pharmaceutical composition having activity of binding to the clostridial toxin receptor. Options of a liquid pharmaceutical composition that does not contain protein excipients and includes an active ingredient in the form of clostridial botulinum toxin; an aqueous carrier; a surfactant that is poloxamer; and methionine are presented. Components are used in the stated quantities. The composition is suitable for subcutaneous or intramuscular injection and is stable for at least one month at 40°C.
EFFECT: use of the group of inventions makes it possible to increase the stability of a pharmaceutical composition having activity of binding to the clostridial toxin receptor.
19 cl, 5 tbl, 3 ex
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