FIELD: medicine.
SUBSTANCE: group of inventions refers to treating bladder dysfunction. Disclosed are methods of introducing composition, containing a therapeutically effective amount of a clostridial neurotoxin derivative into at least one target region under the middle bladder line to reduce or prevent the risk of retention of urination, associated with the treatment of overactive bladder or detrusor neurogenic hyperactivity in the patient with clostridial neurotoxin derivatives or to reduce a patient's need for aseptic intermittent catheterisation (CIC), associated with treatment of overactive bladder or detrusor neurogenic hyperactivity with clostridial neurotoxin derivatives.
EFFECT: group of inventions provides reducing side effects when introducing a clostridial neurotoxin derivative into the urinary bladder.
13 cl, 6 dwg, 5 ex
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CLOSTRIDIAL NEUROTOXINS WITH MODIFIED PERSISTENCE | 2009 |
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RU2524429C2 |
METHOD OF TREATING THE NEUROGENIC BLADDER | 2020 |
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RU2743805C1 |
METHOD OF TREATING DETRUSOR OVERACTIVITY | 2015 |
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RU2605624C1 |
HIGH INTRODUCTION RATE OF NEUROTOXIC COMPONENT OF BOTULINUM TOXIN | 2007 |
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RU2453333C2 |
Authors
Dates
2021-02-01—Published
2017-02-22—Filed